The SCF/Slimb Ubiquitin Ligase Limits Centrosome Amplification through Degradation of SAK/PLK4

Probability-based protein identification by searching sequence databases using mass spectrometry data

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Signal Transduction, Signaling Pathway, Cell Division +6

Plk4-Induced Centriole Biogenesis in Human Cells

Julia Kleylein-Sohn, Jens Westendorf, Mikaël Le Clech et al. · Developmental Cell · 2007 · 675 citations · Full text

Plk4-induced Centriole Biogenesis, Stem Cell Research, Cell Proliferation +3

SAK/PLK4 Is Required for Centriole Duplication and Flagella Development

Mónica Bettencourt‐Dias, Ana Rodrigues-Martins, Lee Carpenter et al. · Current Biology · 2005 · 622 citations · Full text

Genetics, Molecular Genetics, Cloning +3

Centrosome Amplification Can Initiate Tumorigenesis in Flies

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Developmental Biology, Cell Division, Cell Interaction +5