Concepedia

Intramolecular Hydrogen Bonds Preorganize an Aryl-triazole Receptor into a Crescent for Chloride Binding

Semin Lee, Yuran Hua, Hyunsoo Park, Amar H. Flood

Organic Letters · 2010 · 130 citations · 42 references

DOI

Concepts

Abstract

Aryl-triazole pentads have been preorganized with intramolecular hydrogen bonds to enhance chloride binding. This outcome highlights the dual hydrogen bond donor and acceptor properties of 1,2,3-triazoles.

References

42

A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes

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Peptidotriazoles on Solid Phase:  [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides

Christian W. Tornøe, Caspar Christensen, Morten Meldal · The Journal of Organic Chemistry · 2002 · 8.5K citations

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Interconversion of single and double helices formed from synthetic molecular strands

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, , +9

Pure CH Hydrogen Bonding to Chloride Ions: A Preorganized and Rigid Macrocyclic Receptor

Yongjun Li, Amar H. Flood · Angewandte Chemie International Edition · 2008 · 452 citations

, , +17