Up-regulating Blood Brain Barrier Permeability of Nanoparticles via Multivalent Effect

The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassay

A.E. Bolton, W. M. Hunter · Biochemical Journal · 1973 · 3.3K citations · Full text

Life Sciences, Biochemistry, Endocrinology +12

The Binding Avidity of a Nanoparticle-Based Multivalent Targeted Drug Delivery Platform

Seungpyo Hong, Pascale R. Leroueil, István Majoros et al. · Chemistry & Biology · 2007 · 588 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +12

Transferrin- and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood–brain barrier (BBB)

Karsten Ulbrich, Telli Hekmatara, Elisabeth Herbert et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2008 · 584 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +14

Receptor‐mediated transcytosis of transferrin across the blood‐brain barrier

Jordan B. Fishman, Joshua B. Rubin, J. V. Handrahan et al. · Journal of Neuroscience Research · 1987 · 543 citations

Life Sciences, Biochemistry, Neuroscience +17

Identification and Design of Peptides as a New Drug Delivery System for the Brain

Michel Demeule, Anthony Régina, Christian Ché et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 459 citations

Pharmacy, Pharmaceutics, Pharmacology +17