Vascular Endothelial Growth Factor Expression Is Decreased in Rat Lung Following Exposure to 24 or 48 Hours of Hyperoxia

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

B Millauer, Susanne Wizigmann-Voos, Harald Schnürch et al. · Cell · 1993 · 1.9K citations

Developmental Biology, Angiogenesis, Receptor Tyrosine Kinase +9

Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity

Itzhak Hemo, Ahuva Itin, Jacob Pe’er et al. · Nature Medicine · 1995 · 1.6K citations

Survival Factor, Retinal Vessels, Ocular Disease +8

Structural and biochemical changes in rat lungs occurring during exposures to lethal and adaptive doses of oxygen.

James D. Crapo, Brenda E. Barry, H A Foscue et al. · PubMed · 1980 · 668 citations

Acute Lung Injury, Endothelial Cells, Lung Inflammation +23

Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only.

Edi Brogi, Ta‐Peng Wu, Atsushi Namiki et al. · Circulation · 1994 · 546 citations

Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo.

Manabu Kuroki, Emile E. Voest, Shiro Amano et al. · Journal of Clinical Investigation · 1996 · 420 citations · Full text

Redox Biology, Tumor Biology, Oxidative Stress +19