Alteration of the Bcl-x/Bax Ratio in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis: Evidence for the Implication of the p53 Signaling Pathway

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

S M Hsu, Laurence Raine, Herbert Fanger · Journal of Histochemistry & Cytochemistry · 1981 · 14.2K citations · Full text

Immunohematology, Immunocytochemical Technique, Immunology +22

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

D.R. Rosen, Teepu Siddique, David T. Patterson et al. · Nature · 1993 · 7K citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Neurological Disorder +7

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

Zoltán N. Oltval, Curt Milliman, Stanley J. Korsmeyer · Cell · 1993 · 6K citations

Bcl-2 Heterodimerizes, Cell Regulation, Apoptosis +6

Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation

Mark E. Gurney, Haifeng Pu, Arlene Y. Chiu et al. · Science · 1994 · 4.1K citations

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

Toshiyuki Miyashita, John C. Reed · Cell · 1995 · 4.1K citations · Full text

Tumor Biology, Oncogenic Agent, Medicine +10