The factor V Glu1608Lys mutation is recurrent in familial thrombophilia

Mutation in blood coagulation factor V associated with resistance to activated protein C

Rogier M. Bertina, Bobby P. C. Koeleman, Ted Koster et al. · Nature · 1994 · 3.8K citations

Genetics, Pathogenesis, Hematology +6

Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C.

Björn Dahlbäck, Martin Carlsson, Peter J. Svensson · Proceedings of the National Academy of Sciences · 1993 · 2K citations · Full text

Immunology, Genetic Epidemiology, Pathology +21

Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study

Ted Koster, FR Rosendaal, Hans de Ronde et al. · The Lancet · 1993 · 1.3K citations

Thrombopoiesis, Thrombosis, Venous Thrombosis +9

Resistance to Activated Protein C as a Basis for Venous Thrombosis

Peter J. Svensson, Björn Dahlbäck · New England Journal of Medicine · 1994 · 1.1K citations · Full text

Complete cDNA and derived amino acid sequence of human factor V.

Richard J. Jenny, Debra D. Pittman, J J Toole et al. · Proceedings of the National Academy of Sciences · 1987 · 411 citations · Full text

Genetics, Factor V, Human Polymorphism +21