Concepedia

Pharmacokinetic concepts ? Drug binding, apparent volume of distribution and clearance

M. Gibaldi, Jeffrey R. Koup

European Journal of Clinical Pharmacology · 1981 · 92 citations · 14 references

DOI

Concepts

References

14

A physiological approach to hepatic drug clearance

G. Wilkinson, David G. Shand · Clinical Pharmacology & Therapeutics · 1975 · 1.9K citations

, , +17

Clearance concepts in pharmacokinetics

Malcolm Rowland, Leslie Z. Benet, Garry G. Graham · Journal of Pharmacokinetics and Biopharmaceutics · 1973 · 764 citations

, , +10

Animal scale-up

Robert L. Dedrick · Journal of Pharmacokinetics and Biopharmaceutics · 1973 · 394 citations

Prediction of hepatic extraction ratio from in vitro measurement of intrinsic clearance.

A Rane, G. Wilkinson, David G. Shand · Journal of Pharmacology and Experimental Therapeutics · 1977 · 328 citations

, , +17

Apparent volumes of distribution and drug binding to plasma proteins and tissues

M. Gibaldi, Patrick J. McNamara · European Journal of Clinical Pharmacology · 1978 · 107 citations

, , +14