Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

Marco Castagna, Yoshimi Takai, Kozo Kaibuchi et al. · Journal of Biological Chemistry · 1982 · 4.8K citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

A Ullrich, Lisa M. Coussens, Joel S. Hayflick et al. · Nature · 1984 · 2.8K citations

Life Sciences, Genetics, Molecular Biology +7

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

Julian Downward, Yosef Yarden, E. L. V. Mayes et al. · Nature · 1984 · 2.5K citations · Full text

Medicine, Genetics, Molecular Biology +10

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

Tony Hunter, Bartholomew M. Sefton · Proceedings of the National Academy of Sciences · 1980 · 2.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

Andrew S. Kraft, Wayne B. Anderson · Nature · 1983 · 1.3K citations

Life Sciences, Biochemistry, Cell Biology +12