Alleles carried at positions ?819 and ?592 of the IL10 promoter affect transcription following stimulation of peripheral blood cells with Streptococcus pneumoniae

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

René de Waal Malefyt, J S Abrams, B Bennett et al. · The Journal of Experimental Medicine · 1991 · 3.8K citations · Full text

Life Sciences, Immunology, Immunoregulation +10

AN INVESTIGATION OF POLYMORPHISM IN THE INTERLEUKIN‐10 GENE PROMOTER

David M. Turner, Denise Williams, David Sankaran et al. · European Journal of Immunogenetics · 1997 · 1.7K citations

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Genetic influence on cytokine production and fatal meningococcal disease

Rudi GJ Westendorp, Jan A. M. Langermans, T. Huizinga et al. · The Lancet · 1997 · 807 citations

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Polymorphic haplotypes of the interleukin-10 5? flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis

Esther Crawley, Richard Kay, James Sillibourne et al. · Arthritis & Rheumatism · 1999 · 535 citations

Life Sciences, Genetics, Immunology +17

Interleukin 10 secretion in relation to human IL-10 locus haplotypes

Joyce Eskdale, Grant Gallagher, Cor L. Verweij et al. · Proceedings of the National Academy of Sciences · 1998 · 468 citations

Life Sciences, Genetics, Immunology +11