Clinically significant interaction between digoxin and quinidine.

D W Holt, A M Hayler, Michael Edmonds, Richard Ashford

BMJ · 1979 · 16 citations · 2 references

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Abstract

paras), and to attend a clinic or return the questionnaire after three months.Fifty-two patients (87 %) (15 primiparas and 37 multiparas) completed questionnaires.They were matched with a control group of 52 vaccinated patients who received no hormonal treatment.The mean (i SD) number of days of postpartum bleeding was 58-5 i 18-5 in the treated patients and 20-8 1-1 in the controls.This difference was significant (P <0-001).Patients still bleeding at three months were treated with low-dose oestrogen/ progestogen pills) which invariably stopped bleeding.Only one patient was so treated before three months.Thirty-three treated patients, but only two controls, had continuous bleeding for three months.In no case was the loss heavy and no patients developed anaemia (haemoglobin less than 10-0 g/dl).

References

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