Accumulation of Dynamic Catch Bonds between TCR and Agonist Peptide-MHC Triggers T Cell Signaling

A Threshold Selection Method from Gray-Level Histograms

Nobuyuki Otsu · IEEE Transactions on Systems Man and Cybernetics · 1979 · 42.3K citations

Image Analysis, Machine Vision, Engineering +8

T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

Thorsten R. Mempel, Sarah E. Henrickson, Ulrich H. von Andrian · Nature · 2004 · 1.7K citations · Full text

Autoimmune Disease, Adaptive Immune System, Distinct Phases +12

Direct observation of catch bonds involving cell-adhesion molecules

Bryan T. Marshall, Mian Long, James W. Piper et al. · Nature · 2003 · 996 citations · Full text

Proteinlipid Interaction, Cell Adhesion, Direct Observation +4

Kinetic proofreading in T-cell receptor signal transduction.

Timothy W. McKeithan · Proceedings of the National Academy of Sciences · 1995 · 964 citations · Full text

T-regulatory Cell, Immunology, Immunodominance +18

Tracking kinesin-driven movements with nanometre-scale precision

Jeff Gelles, Bruce J. Schnapp, Michael P. Sheetz · Nature · 1988 · 816 citations

Kinesiology, Engineering, Kinesin-driven Movements +9