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HIF-1α Inhibition Reverses Multidrug Resistance in Colon Cancer Cells via Downregulation of MDR1/P-Glycoprotein

DOIFull Paper Access

154

Citations

28

References

2014

Year

Jianfang Chen, Zhenyu Ding, Yonghai Peng, Feng Pan, Jianjun Li, Lan Zou, Yanling Zhang, Houjie Liang
PLoS ONE

Abstract

HIF-1α inhibition reverses multidrug resistance in colon cancer cells via downregulation of MDR1/P-gp. The expression of HIF-1α and MDR1/P-gp can be used as a predictive marker for chemotherapy resistance in colon cancer.

References

YearCitations

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