Synthesis and antiproliferative activities of diversely substituted glycosyl-isoindigo derivatives

Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity

John O’Brien, Ian D. Wilson, Terry C. Orton et al. · European Journal of Biochemistry · 2000 · 3.4K citations · Full text

Dentistry, Biochemistry, Cell Biology +14

Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease

Sophie Leclerc, Matthieu Garnier, Ralph Hoessel et al. · Journal of Biological Chemistry · 2001 · 723 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +13

Discovery of 5-[5-Fluoro-2-oxo-1,2- dihydroindol-(3<i>Z</i>)-ylidenemethyl]-2,4- dimethyl-1<i>H</i>-pyrrole-3-carboxylic Acid (2-Diethylaminoethyl)amide, a Novel Tyrosine Kinase Inhibitor Targeting Vascular Endothelial and Platelet-Derived Growth Factor Receptor Tyrosine Kinase

Li Sun, Chris Liang, Sheri Shirazian et al. · Journal of Medicinal Chemistry · 2003 · 520 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Indirubin and Indigo Are Potent Aryl Hydrocarbon Receptor Ligands Present in Human Urine

Jun Adachi, Y. Mori, Saburo Matsui et al. · Journal of Biological Chemistry · 2001 · 406 citations · Full text

Medicine, Biochemistry, Pharmacology +11

DNA fluorometric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distilled water

Randall Rage, Jacque Mitchen, George Wilding · Analytical Biochemistry · 1990 · 393 citations

Life Sciences, Cell Biology, Molecular Biology +9