The Regional Oxygen Saturation of Pituitary Adenomas Is Lower than That of the Pituitary Gland: Microspectrophotometric Study with Potential Clinical Implications

Abstract

As assessed with MSP measurements, the rSO(2) of adenoma tissue was significantly lower than that of the pituitary gland, indicating differences in their blood supply and/or metabolism in pituitary macroadenomas. Further studies are needed to determine whether MSP measurements can reliably facilitate intraoperative delineation of adenoma and pituitary tissue, in the effort to achieve complete tumor removal with minimal injury to pituitary tissue.