Negative Immunoregulatory Effects of Antidepressants Inhibition of Interferon-γ and Stimulation of Interleukin-10 Secretion

The macrophage theory of depression

R.S. Smith · Medical Hypotheses · 1991 · 934 citations

Life Sciences, Immunology, Psychology +10

THE EFFECTS OF PSYCHOLOGICAL STRESS ON HUMANS: INCREASED PRODUCTION OF PRO-INFLAMMATORY CYTOKINES AND Th1-LIKE RESPONSE IN STRESS-INDUCED ANXIETY

Michaël Maes, Cai Song, Aihua Lin et al. · Cytokine · 1998 · 772 citations

Nursing, Immunology, Psychology +12

Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression

Michaël Maes, Herbert Y. Meltzer, Eugène Bosmans et al. · Journal of Affective Disorders · 1995 · 629 citations

Nursing, Immunology, Psychiatry +14

Endotoxin produces a depressive-like episode in rats

Raz Yirmiya · Brain Research · 1996 · 581 citations

Nursing, Neuroscience, Pharmacology +10

Direct stimulation of cytokines (IL-1β, TNF-α, IL-6, IL-2, IFN-γ and GM-CSF) in whole blood. I. Comparison with isolated PBMC stimulation

D De Groote, P.F. Zangerle, Y. Gevaert et al. · Cytokine · 1992 · 473 citations

Life Sciences, Hematology, Immunology +10