Involvement of SPARC and MMP-3 in the Pathogenesis of Human Pterygium - Concepedia

Concepedia

Publication | Open Access

Involvement of SPARC and MMP-3 in the Pathogenesis of Human Pterygium

DOI Full Paper Access

48

Citations

19

References

2012

Year

Li‐Fong Seet, Louis Tong, Roseline Su, Tina Wong

Investigative Ophthalmology & Visual Science

Abstract

SPARC was upregulated in pterygium and may collaborate with increased MMP-3 in some patients to account for many of the phenotypic properties characteristic of pterygium.

References

	Year	Citations
SPARC, a secreted protein associated with morphogenesis and tissue remodeling, induces expression of metalloproteinases in fibroblasts through a novel extracellular matrix-dependent pathway. Patrice Tremble, Timothy F. Lane, E. Helene Sage, The Journal of Cell Biology Tissue EngineeringEngineeringCollagen TypesPathologyCellular Physiology	1993	280
The role of SPARC in extracellular matrix assembly Amy D. Bradshaw Journal of Cell Communication and Signaling Cell AdhesionMolecular BiologyBiomedical EngineeringCellular PhysiologyEcm Deposition	2009	242
SPARC/osteonectin induces matrix metalloproteinase 2 activation in human breast cancer cell lines. Christine Gilles, James A. Bassuk, Helena Pulyaeva, PubMed Breast OncologyCell AdhesionPathologyCytoskeletonCancer Biology	1998	206
Enhanced expression of SPARC/osteonectin in the tumor-associated stroma of non-small cell lung cancer is correlated with markers of hypoxia/acidity and with poor prognosis of patients. Michael I. Koukourakis, Alexandra Giatromanolaki, Rolf A. Brekken, PubMed PathologyCancer BiologyTumor BiologyTissue DevelopmentMatrix Biology	2003	197
Cleavage of the Matricellular Protein SPARC by Matrix Metalloproteinase 3 Produces Polypeptides That Influence Angiogenesis E. Helene Sage, May J. Reed, Sarah E. Funk, Journal of Biological Chemistry	2003	171
Overexpression of collagenase (MMP-1) and stromelysin (MMP-3) by pterygium head fibroblasts. De Quan Li, Seong‐Beom Lee, Zeenat Gunja‐Smith, PubMed	2001	122
Supramolecular Interactions in the Dermo-epidermal Junction Zone Daniela Villone, Anja Fritsch, Manuel Koch, Journal of Biological Chemistry	2008	121
SPARC (secreted protein acidic and rich in cysteine) regulates endothelial cell shape and barrier function. Simeon E. Goldblum, Xuefeng Ding, Sarah E. Funk, Proceedings of the National Academy of Sciences	1994	118
Expression of SPARC during development of the chicken chorioallantoic membrane: evidence for regulated proteolysis in vivo. M. Luisa Iruela‐Arispe, Timothy F. Lane, Diane Redmond, Molecular Biology of the Cell Protein SecretionCellular PhysiologyRegulated ProteolysisAngiogenesisPlasmin Activity	1995	104
SPARC upregulates MT1-MMP expression, MMP-2 activation, and the secretion and cleavage of galectin-3 in U87MG glioma cells Heather McClung, Stacey L. Thomas, Pamela Osenkowski, Neuroscience Letters GliomaMedicineImmunologyU87mg Glioma CellsTumor Suppressor	2007	94

Page 1