In vitro and in vivo pharmacology of S 16474, a novel dual tachykinin NK1 and NK2 receptor antagonist

A Potent Nonpeptide Antagonist of the Substance P (NK ₁ ) Receptor

R. Michael Snider, Jay W. Constantine, John Lowe et al. · Science · 1991 · 864 citations

Medicine, Medicinal Chemistry, Pharmacology +14

cDNA eloping of bovine substance-K receptor through oocyte expression system

Yasuo Masu, Kazuhisa Nakayama, Hiromi Tamaki et al. · Nature · 1987 · 743 citations

Life Sciences, Biochemistry, Molecular Biology +7

Molecular characterization of a functional cDNA for rat substance P receptor

Yoshifumi Yokota, Yoshiki Sasai, Kazuo Tanaka et al. · Journal of Biological Chemistry · 1989 · 457 citations · Full text

Medicine, Molecular Biology, Pharmacology +15

A potent and selective non-peptide antagonist of the neurokinin a (NK2) receptor

Xavier Emonds‐Alt, P. Vilain, P. Goulaouic et al. · Life Sciences · 1992 · 437 citations

Medicine, Neuroscience, Pharmacology +5

A substance P antagonist inhibits vagally induced increase in vascular permeability and bronchial smooth muscle contraction in the guinea pig

Jan M. Lundberg, Alois Saria, Ernst Brodin et al. · Proceedings of the National Academy of Sciences · 1983 · 436 citations · Full text

Medicine, Pharmacology, Clinical Pharmacology +13