BJOG An International Journal of Obstetrics & Gynaecology · 2000 · 91 citations · 14 references
MedicineMaternal HealthObstetricsHigh-risk PregnancyMaternal-fetal MedicinePrenatal DiagnosisAntenatal Risk AssessmentPregnancyPrenatal AssessmentPrenatal CarePrenatal Genetic DiagnosisPrenatal Risk AssessmentFirst Trimester UltrasonographyObstetric Risk ScreeningPrenatal Anomaly ScreeningPrenatal Diagnosis Of Down SyndromePrenatal ScreeningPrenatal Screening CounselingPrenatal Screening Decision-makingRisk Screening In Pregnancy
One hundred women were interviewed at their first hospital antenatal visit to assess their knowledge of, and attitudes to, first versus second trimester screening for Down's syndrome. Overall, the women had limited knowledge of Down's syndrome, and the prenatal screening and diagnostic tests that are available. However, when informed, the majority of women expressed a clear preference for first trimester screening tests for Down's syndrome, regardless of the rate of miscarriage of Down's syndrome pregnancies between 10 and 15 weeks of gestation. These findings have implications for the planning of prenatal Down's syndrome screening programmes.
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Kevin Spencer, Vivienne Souter, Natasha Tul et al. · Ultrasound in Obstetrics and Gynecology · 1999 · 571 citations
Dimeric Inhibin A as a Marker for Down's Syndrome in Early Pregnancy
David A. Aitken, Euan M. Wallace, Jennifer A. Crossley et al. · New England Journal of Medicine · 1996 · 182 citations
Medicine, Endocrinology, Obstetrics +15
Jane Halliday, Lyndsey F. Watson, Judith Lumley et al. · Prenatal Diagnosis · 1995 · 131 citations