Concepedia

Dimeric Inhibin A as a Marker for Down's Syndrome in Early Pregnancy

David A. Aitken, Euan M. Wallace, Jennifer A. Crossley, I. A. Swanston, Yvonne van Pareren, Merel van Maarle, Nigel P. Groome, James N. Macri, J. M. Connor

New England Journal of Medicine · 1996 · 182 citations · 41 references

DOI

Abstract

In the second trimester of pregnancy, measuring inhibin A in maternal serum, in combination with measurements of alpha-fetoprotein and beta subunit of human chorionic gonadotropin, significantly improved the rate of detection of Down's syndrome.

References

41

Maternal serum screening for Down's syndrome in early pregnancy.

N J Wald, Howard Cuckle, J. W. Densem et al. · BMJ · 1988 · 974 citations · Full text

, , +16

An association between low maternal serum α-fetoprotein and fetal chromosomal abnormalities

Irwin R. Merkatz, Harold M. Nitowsky, James N. Macri et al. · American Journal of Obstetrics and Gynecology · 1984 · 739 citations

, , +11

Abnormal maternal serum chorionic gonadotropin levels in pregnancies with fetal chromosome abnormalities

Mark H. Bogart, M.R. Pandian, Oliver W. Jones · Prenatal Diagnosis · 1987 · 473 citations

Prenatal Screening for Down's Syndrome with Use of Maternal Serum Markers

James E. Haddow, Glenn E. Palomaki, George J. Knight et al. · New England Journal of Medicine · 1992 · 460 citations · Full text

Detection of dimeric inhibin throughout the human menstrual cycle by two‐site enzyme immunoassay

Nigel P. Groome, Peter Illingworth, Margaret O’Brien et al. · Clinical Endocrinology · 1994 · 373 citations