Demonstrating efficacy in preclinical studies of cellular therapies for spinal cord injury — How much is enough?

1,026 Experimental treatments in acute stroke

Victoria O’Collins, Malcolm Macleod, Geoffrey A. Donnan et al. · Annals of Neurology · 2006 · 1.4K citations

Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitor Cell Transplants Remyelinate and Restore Locomotion after Spinal Cord Injury

Hans S. Keirstead, Gabriel Nistor, Giovanna M. Bernal et al. · Journal of Neuroscience · 2005 · 1.2K citations · Full text

Myelin-forming Cells, Biomedical Engineering, Social Sciences +18

Long-Distance Growth and Connectivity of Neural Stem Cells after Severe Spinal Cord Injury

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Regenerative Medicine, Neuroregeneration, Developmental Biology +15

Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats

Otto Rapalino, Orly Lazarov, Eugenia Agranov et al. · Nature Medicine · 1998 · 787 citations

Regenerative Medicine, Inflammation, Neuroregeneration +13

Can experiments in nonhuman primates expedite the translation of treatments for spinal cord injury in humans?

Grégoire Courtine, Mary Bartlett Bunge, James W. Fawcett et al. · Nature Medicine · 2007 · 382 citations · Full text

Spinal Cord Injury, Peripheral Nerve Injury, Spinal Biomechanics +14