Opioid antagonists and butorphanol dependence

The rat brain in stereotaxic coordinates

Miklós Palkovits · Neuropeptides · 1983 · 29K citations

Medicine, Neurobiology, Neuroscience +12

Naltrindole, a highly selective and potent non-peptide δ opioid receptor antagonist

Philip S. Portoghese, Marjia Sultana, A.E. Takemori · European Journal of Pharmacology · 1988 · 613 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Selective blockage of delta opioid receptors prevents the development of morphine tolerance and dependence in mice.

Essam E. Abdelhamid, Marjia Sultana, Philip S. Portoghese et al. · Journal of Pharmacology and Experimental Therapeutics · 1991 · 427 citations

Medicine, Pharmacology, Neuropharmacology +16

Application of the message-address concept in the design of highly potent and selective non-peptide .delta. opioid receptor antagonists

P. S. Portoghese, Marjia Sultana, Hiroshi Nagase et al. · Journal of Medicinal Chemistry · 1988 · 305 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Pharmacological characterization in vivo of the novel opiate, beta-funaltrexamine.

Susan J. Ward, Philip S. Portoghese, A.E. Takemori · Journal of Pharmacology and Experimental Therapeutics · 1982 · 302 citations

Medicine, Medicinal Chemistry, Pharmacology +17