Diamond-Blackfan Syndrome: Lymphocyte-Mediated Suppression of Erythropoiesis

Ronald Hoffman, Esmail D. Zanjani, José M. Vila, Ralph Zalusky, J. D. Lutton, Louis R. Wasserman

Science · 1976 · 146 citations · 15 references

Concepts

Abstract

Peripheral blood lymphocytes from six patients with congenital hypoplastic anemia suppressed erythroid cell formation by normal human bone marrow cells in response to erythropoietin in vitro. The results suggest that the anemia in these children has an immunologic basis.

References

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