Concepedia

Pharmacokinetics of an anti-TFPI monoclonal antibody (concizumab) blocking the TFPI interaction with the active site of FXa in Cynomolgus monkeys after iv and sc administration

Henrik Agersø, Rune Viig Overgaard, Mads Bjelke Petersen, Lene Hansen, Mette B. Hermit, Mette Høgh Sørensen, Lars C. Petersen, Ida Hilden

European Journal of Pharmaceutical Sciences · 2014 · 40 citations · 11 references

DOI

Concepts

References

11

Monoclonal Antibody Pharmacokinetics and Pharmacodynamics

Wenhui Wang, EQ Wang, JP Balthasar · Clinical Pharmacology & Therapeutics · 2008 · 954 citations

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General Pharmacokinetic Model for Drugs Exhibiting Target-Mediated Drug Disposition

Donald E. Mager, William J. Jusko · Journal of Pharmacokinetics and Pharmacodynamics · 2001 · 587 citations

, , +14

A Theoretical Model of γ-Globulin Catabolism

F. W. Rogers Brambell, W. A. Hemmings, Ian Morris · Nature · 1964 · 441 citations

, , +2

MHC Class I-Related Neonatal Fc Receptor for IgG Is Functionally Expressed in Monocytes, Intestinal Macrophages, and Dendritic Cells

Xiaoping Zhu, Gang Meng, Bonny L. Dickinson et al. · The Journal of Immunology · 2001 · 315 citations · Full text

, , +16

Approximations of the target-mediated drug disposition model and identifiability of model parameters

Leonid Gibiansky, Ekaterina Gibiansky, Tarundeep Kakkar et al. · Journal of Pharmacokinetics and Pharmacodynamics · 2008 · 264 citations

, , +14