Concepedia

Mutations in the human Sonic Hedgehog gene cause holoprosencephaly

Erich Roessler, Elena Belloni, Karin Gaudenz, Philippe Jay, Philippe Berta, Stephen W. Scherer, Lap‐Chee Tsui, Maximilian Muenke

Nature Genetics · 1996 · 1.2K citations · 35 references

DOI

Concepts

References

35

Mutations affecting segment number and polarity in Drosophila

Christiane Nüsslein‐Volhard, Eric Wieschaus · Nature · 1980 · 4.4K citations

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Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

Chin Chiang, Ying Litingtung, Eric Lee et al. · Nature · 1996 · 3.1K citations

, , +14

Sonic hedgehog mediates the polarizing activity of the ZPA

Robert D. Riddle, Randy L. Johnson, Ed Laufer et al. · Cell · 1993 · 2.3K citations

, , +10

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

Yann Echelard, Douglas J. Epstein, Benoit St‐Jacques et al. · Cell · 1993 · 2.2K citations

, , +13

A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos

Jean‐Paul Concordet, Philip W. Ingham · Cell · 1993 · 1.1K citations

, , +14