A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos

A simple method for displaying the hydropathic character of a protein

Jack Kyte, Russell F. Doolittle · Journal of Molecular Biology · 1982 · 23.1K citations

Life Sciences, Biochemistry, Molecular Biology +12

A new method for predicting signal sequence cleavage sites

Gunnar von Heijne · Nucleic Acids Research · 1986 · 4.6K citations · Full text

Life Sciences, Bioinformatics, Biology +11

Mutations affecting segment number and polarity in Drosophila

Christiane Nüsslein‐Volhard, Eric Wieschaus · Nature · 1980 · 4.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Sonic hedgehog mediates the polarizing activity of the ZPA

Robert D. Riddle, Randy L. Johnson, Ed Laufer et al. · Cell · 1993 · 2.3K citations

Life Sciences, Cell Biology, Developmental Biology +10

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

Yann Echelard, Douglas J. Epstein, Benoit St‐Jacques et al. · Cell · 1993 · 2.2K citations

Life Sciences, Neurobiology, Neuroscience +13