Attenuation of the vasoconstrictor effects of thromboxane and endothelin by nitric oxide in the human fetal-placental circulation

Vascular endothelial cells synthesize nitric oxide from L-arginine

Richard Palmer, D. Ashton, Salvador Moncada · Nature · 1988 · 4.8K citations

Inflammation, Reactive Nitrogen Specie, Physiology +7

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

David S. Bredt, Solomon H. Snyder · Proceedings of the National Academy of Sciences · 1990 · 3.3K citations

Nitric Oxide, Chemical Biology, Redox Biology +17

Localization of nitric oxide synthase indicating a neural role for nitric oxide

David S. Bredt, Paul M. Hwang, Solomon H. Snyder · Nature · 1990 · 3K citations

Neurophysiology, Neuroanatomy, Nitric Oxide +11

Endothelium‐derived relaxing and contracting factors

Robert F. Furchgott, Paul M. Vanhoutte · The FASEB Journal · 1989 · 2K citations

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

L J Ignarro, Howard Lippton, Jo C. W. Edwards et al. · Journal of Pharmacology and Experimental Therapeutics · 1981 · 1.6K citations

Reactive Nitrogen Specie, Nitric Oxide, Medicine +8