International Journal of Infectious Diseases · 2015 · 67 citations · 8 references
Life SciencesInfectious DiseasesMicrobiologyBacteriologyEnvironmental MicrobiologySepsis16S Ribosomal Ribonucleic Acid AnalysisBacterial IdentificationBacterial InfectionsEnvironmental BacteriologyMicrobial ContaminationPathogen DetectionBacillus SphaericusClinical Bacterial IdentificationMass Spectrometry-based IdentificationMass Spectrometry-based Microbial IdentificationMatrix-assisted Laser Desorption/ionizationPersistent BacteremiaTime-of-flight Mass SpectrometryTime-of-flight Spectroscopy
Lysinibacillus and Paenibacillus are pervasive bacteria rarely associated with human disease. Less sophisticated microbiology techniques may frequently incorrectly identify these genera as Bacillus spp., often regarded as environmental contamination. This report describes a case of severe sepsis due to persistent Lysinibacillus and Paenibacillus bacteremia, identified by matrix-assisted laser desorption and ionization time-of-flight mass spectroscopy and 16S rRNA gene sequencing.
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