Interaction of anticancer drug methotrexate with DNA analyzed by electrochemical and spectroscopic methods

Temporary Remissions in Acute Leukemia in Children Produced by Folic Acid Antagonist, 4-Aminopteroyl-Glutamic Acid (Aminopterin)

Sidney Farber, Louis K. Diamond, Robert D. Mercer et al. · New England Journal of Medicine · 1948 · 1.8K citations

Pharmacy, Pharmacology, Pharmacotherapy +11

Voltammetric studies of the interaction of metal chelates with DNA. 2. Tris-chelated complexes of cobalt(III) and iron(II) with 1,10-phenanthroline and 2,2'-bipyridine

Michael T. Carter, Marisol Rodriguez, Allen J. Bard · Journal of the American Chemical Society · 1989 · 1.6K citations

Natural Sciences, Biochemistry, Chemistry +14

New Approaches to Cancer Chemotherapy with Methotrexate

Howard L. Bleich, Emily S. Boro, E Frei et al. · New England Journal of Medicine · 1975 · 232 citations

Medicine, Oncology, Pharmacology +16

Voltammetric studies of the interaction of nogalamycin antitumor drug with DNA

Mohamed Ibrahim · Analytica Chimica Acta · 2001 · 165 citations

Medicine, Medicinal Chemistry, Oncology +6

Improved therapeutic index of methotrexate with "leucovorin rescue".

Martin Levitt, Mosher Mb, DeConti Rc et al. · PubMed · 1973 · 151 citations

Medicine, Oncology, Pharmacology +9