Venous dilator effect of apelin, an endogenous peptide ligand for the orphan APJ receptor, in conscious rats

Isolation and Characterization of a Novel Endogenous Peptide Ligand for the Human APJ Receptor

Kazuhiko Tatemoto, Masaki Hosoya, Yugo Habata et al. · Biochemical and Biophysical Research Communications · 1998 · 1.7K citations

Medicine, Medicinal Chemistry, Pharmacology +10

A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11

Brian F. O’Dowd, Michael Heiber, Audrey Chan et al. · Gene · 1993 · 840 citations

Life Sciences, Genetics, Molecular Genetics +5

Characterization of Apelin, the Ligand for the APJ Receptor

Dennis K. Lee, Regina Cheng, Tuan Nguyen et al. · Journal of Neurochemistry · 2000 · 676 citations

Life Sciences, Neuroscience, Physiology +12

The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism

Kazuhiko Tatemoto, Kiyoshige Takayama, Iku Kumaki et al. · Regulatory Peptides · 2001 · 643 citations

Medicine, Cardiology, Physiology +14

Apelin, the Novel Endogenous Ligand of the Orphan Receptor APJ, Regulates Cardiac Contractility

István Szokodi, Pasi Tavi, Gábor Földes et al. · Circulation Research · 2002 · 617 citations

Life Sciences, Pharmacology, Physiology +11