JAMA · 1967 · 15 citations · 7 references
MedicineNephrologyPharmacologyDialysisHemodialysisRenal Replacement TherapyDialysis PharmacotherapyDrug DispositionDrug RemovalHemodialysis ComplicationsRenal Replacement Therapy PharmacologyRenal ToxicityDialysate Drug RemovalDialysis RemovalDose Adjustment During HemodialysisDrug Clearance By HemodialysisDrug Clearance During HemodialysisHemodialysis PharmacokineticsPharmacokinetics In Dialysis
A 43-year-old woman underwent hemodialysis for excessive ingestion of a number of drugs including chlordiazepoxide hydrochloride (Librium), barbiturates, ethchlorvynol (Placidyl), and alcohol. During the dialysis the patient improved, and the plasma level of chlordiazepoxide decreased, which suggested that hemodialysis can be used to remove this drug from the body.
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Experimental and clinical toxicology of chlordiazepoxide (Librium®)
G. Zbinden, Robert E. Bagdon, Eaden F. Keith et al. · Toxicology and Applied Pharmacology · 1961 · 45 citations
Ethchlorvynol (Placidyl®) Intoxication
Frederic B. Westervelt · Annals of Internal Medicine · 1966 · 22 citations
Medicine, Pharmacology, Toxicology +16
Chemical Findings in Poisonings
Arthur J. McBay · New England Journal of Medicine · 1966 · 19 citations