The American Journal of Gastroenterology · 2005 · 81 citations · 37 references
MedicinePediatricsSurgeryChild NutritionGastroenterologyPediatric NutritionEnteral FeedingEnteral NutritionGastroesophageal Reflux DiseaseGastrointestinal InterventionsGastrointestinal SurgeryPediatric Surgical NutritionEnteral Feeding CareEnteral Feeding TubesJejunostomy Tube PlacementMechanical Failure CriteriaPediatric Enteral FeedingPediatric Gastroesophageal Reflux DiseasePostpyloric FeedingRetrospective Record Review
BACKGROUND: A gastro-jejunal (G-J) feeding tube is a safe and useful temporizing method of providing enteral access in children. Although G-J tubes are often used to obviate the need for a surgical jejunostomy, their long-term use is often associated with mechanical failure. AIM: To review the clinically effective durability of G-J feeding tubes in providing enteral access in children. METHODS: We performed a retrospective review of 102 patients at the Johns Hopkins Children's Center from 1994-2003 whose underlying diagnosis necessitated the need for postpyloric enteral access. RESULTS: Long-term follow-up was obtained in 85 (48 M; 37 F) patients with a median (range) age of 2.0 (0.1-18.0) yr. The most common indication for G-J tube placement was gastroesophageal reflux with aspiration in 51 patients and feeding intolerance and vomiting in 19 patients. The mean (range) number of tube replacements was 2.2 (1-14) over a median (range) duration of follow-up of 39 (2-474) days. The indication for G-J tube replacement included: tube displacement (58), a clogged tube (41), and a cracked tube or ruptured balloon (35). In 52 cases, the cause for G-J tube replacement was undetermined. CONCLUSIONS: G-J feeding tubes are associated with the frequent need for tube maintenance and replacement and may not be the most feasible clinical option in providing long-term (>1 month) enteral access in children intolerant to gastrostomy tube feeds. Future studies are needed to develop innovative percutaneous jejunostomy tube placement techniques that facilitate long-term enteral access.
37
Role of Oral Intake in Maintenance of Gut Mass and Disaccharide Activity
Gary M. Levine, Julius J. Deren, Ezra Steiger et al. · Gastroenterology · 1974 · 500 citations
The Effect of Parenteral Nutrition on Gastrointestinal Immunity
John C. Alverdy, Hoon Sang, George F. Sheldon · Annals of Surgery · 1985 · 349 citations · Full text
Agriculture, Immunology, Nutrition +16