Concepedia

Ginsenoside Rb1 inhibits fibrillation and toxicity of alpha-synuclein and disaggregates preformed fibrils

Mustafa T. Ardah, Katerina E. Paleologou, Guohua Lv, Sindhu Menon, Salema B. Abul Khair, Jiahong Lu, Bared Safieh‐Garabedian, Abdulmonem A. Al-Hayani, David Eliezer, Min Li,

Neurobiology of Disease · 2014 · 107 citations · 35 references

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35

α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies

Maria Grazia Spillantini, R. Anthony Crowther, Ross Jakes et al. · Proceedings of the National Academy of Sciences · 1998 · 3.2K citations

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Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

Kelvin C. Luk, Victoria Kehm, Jenna C. Carroll et al. · Science · 2012 · 2.6K citations

, , +17

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

Masaya Baba, Shigeo Nakajo, Pang‐Hsien Tu et al. · PubMed · 1998 · 1.6K citations

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Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death

Laura A. Volpicelli‐Daley, Kelvin C. Luk, Tapan P. Patel et al. · Neuron · 2011 · 1.6K citations · Full text

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Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy

Kelly A. Conway, Seung‐Jae Lee, Jean‐Christophe Rochet et al. · Proceedings of the National Academy of Sciences · 2000 · 1.5K citations

, , +17