Long-term imipramine withdrawal induces a depressive-like behaviour in the forced swimming test

Goodman and Gilman's the Pharmacological Basis of Therapeutics

William H. Stigelman, D Pharm · Military Medicine · 1986 · 6.8K citations

Medicine, Pharmacology, Pharmacotherapy +6

Behavioural despair in rats: A new model sensitive to antidepressant treatments

Roger D. Porsolt, Guy Anton, N. Blavet et al. · European Journal of Pharmacology · 1978 · 3.1K citations

Medicine, Behavioral Sciences, Neurobiology +13

Goodman and Gilman's The Pharmacological Basis of Therapeutics

Robert C. Hastings · JAMA · 1996 · 2.4K citations

Medicine, Pharmacology, Pharmacotherapy +6

Continuation drug therapy for major depressive episodes: how long should it be maintained?

Robert F. Prien, David J. Kupfer · American Journal of Psychiatry · 1986 · 297 citations

Pharmacy, Pharmacotherapy, Psychiatry +17

The alpha(2a)-adrenergic receptor plays a protective role in mouse behavioral models of depression and anxiety.

Nicole Schramm, Michael P. McDonald, L E Limbird · PubMed · 2001 · 219 citations · Full text

Medicine, Neuroscience, Pharmacology +15