Fibroblasts Show More Potential as Target Cells than Keratinocytes in COL7A1 Gene Therapy of Dystrophic Epidermolysis Bullosa

Seria cultivation of strains of human epidemal keratinocytes: the formation keratinizin colonies from single cell is

James G. Rheinwatd, Howard Green · Cell · 1975 · 4.5K citations

Life Sciences, Cell Biology, Microbiology +6

Nonviral Transfer of the Gene Encoding Coagulation Factor VIII in Patients with Severe Hemophilia A

David A. Roth, Nicholas E. Tawa, Joanne O’Brien et al. · New England Journal of Medicine · 2001 · 366 citations · Full text

Medicine, Genetics, Hematology +15

Stable nonviral genetic correction of inherited human skin disease

Susana Ortiz‐Urda, Bhaskar Thyagarajan, Douglas R. Keene et al. · Nature Medicine · 2002 · 246 citations

Medicine, Dermatology, Genetics +14

Cloning of human type VII collagen. Complete primary sequence of the alpha 1(VII) chain and identification of intragenic polymorphisms.

Angela M. Christiano, Daniel S. Greenspan, Seungbok Lee et al. · Journal of Biological Chemistry · 1994 · 210 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa

Mei Chen, Noriyuki Kasahara, Douglas R. Keene et al. · Nature Genetics · 2002 · 198 citations

Medicine, Dermatology, Pathology +9