TRF2 overexpression diminishes repair of telomeric single-strand breaks and accelerates telomere shortening in human fibroblasts

Oxidative stress shortens telomeres

Thomas von Zglinicki · Trends in Biochemical Sciences · 2002 · 2.5K citations

Reactive Oxygen Specie, Medicine, Cell Biology +2

Mammalian Telomeres End in a Large Duplex Loop

Jack D. Griffith, Laurey Comeau, Soraya I. Rosenfield et al. · Cell · 1999 · 2.4K citations · Full text

Chromatin, Genome Instability, Cell Division +7

TRF2 Protects Human Telomeres from End-to-End Fusions

Bas van Steensel, Agata Smogorzewska, Titia de Lange · Cell · 1998 · 1.7K citations · Full text

Genome Instability, Human Cell, Medicine +2

DNA Damage Foci at Dysfunctional Telomeres

Hiroyuki Takai, Agata Smogorzewska, Titia de Lange · Current Biology · 2003 · 1.4K citations · Full text

Chromatin, Genome Instability, Dna Damage +8

Senescence Induced by Altered Telomere State, Not Telomere Loss

Jan Karlseder, Agata Smogorzewska, Titia de Lange · Science · 2002 · 789 citations

Lifespan Extension, Chromatin, Genome Instability +14