Concepedia

Human Multidrug Resistance Protein 2 Transports the Therapeutic Bile Salt Tauroursodeoxycholate

Phillip M. Gerk, Wei Li, Vandana Megaraj, Mary Vore

Journal of Pharmacology and Experimental Therapeutics · 2006 · 40 citations · 30 references

DOI

Concepts

References

30

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.

Raymond Evers, Marcel Kool, Liesbeth van Deemter et al. · Journal of Clinical Investigation · 1998 · 615 citations · Full text

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Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver

Bruno Stieger, Karin Fattinger, Jerzy Madon et al. · Gastroenterology · 2000 · 583 citations · Full text

, , +13

Quantitative estimation of the hydrophilic-hydrophobic balance of mixed bile salt solutions.

Douglas M. Heuman · Journal of Lipid Research · 1989 · 549 citations · Full text

, , +12

Structural Basis of Multiple Drug-Binding Capacity of the AcrB Multidrug Efflux Pump

Edward Yu, Gerry McDermott, Helen I. Zgurskaya et al. · Science · 2003 · 392 citations

, , +17

Cotransport of Reduced Glutathione With Bile Salts by Mrp4 (Abcc4) Localized to the Basolateral Hepatocyte Membrane

Maria Rius, Anne T. Nies, Johanna Hummel-Eisenbeiss et al. · Hepatology · 2003 · 361 citations · Full text

, , +17