Hydrazones of 1,2-benzisothiazole hydrazides: synthesis, antimicrobial activity and QSAR investigations

Manual of Clinical Microbiology.

Annals of Internal Medicine · 1980 · 14.5K citations

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Development and use of quantum mechanical molecular models. 76. AM1: a new general purpose quantum mechanical molecular model

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Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

Anthony Nicholls, Kim A. Sharp, Barry Honig · Proteins Structure Function and Bioinformatics · 1991 · 5.2K citations

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Molecular Similarity Indices in a Comparative Analysis (CoMSIA) of Drug Molecules to Correlate and Predict Their Biological Activity

G. Klebe, Ute Abraham, Thomas Mietzner · Journal of Medicinal Chemistry · 1994 · 1.8K citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Crossvalidation, Bootstrapping, and Partial Least Squares Compared with Multiple Regression in Conventional QSAR Studies

Richard D. Cramer, Jeffrey D. Bunce, David E. Patterson et al. · Quantitative Structure-Activity Relationships · 1988 · 840 citations

Pharmacy, Medicinal Chemistry, Drug Design +9