Expression of Smad2 and Smad4 in cervical cancer: absent nuclear Smad4 expression correlates with poor survival

<i>DPC4</i> , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1

Stephan A. Hahn, Mieke Schutte, A.T.M. Shamsul Hoque et al. · Science · 1996 · 2.3K citations

Medicine, Genetics, Oncology +17

MADR2 Maps to 18q21 and Encodes a TGFβ–Regulated MAD–Related Protein That Is Functionally Mutated in Colorectal Carcinoma

Kolja Eppert, Stephen W. Scherer, Hilmi Özçelik et al. · Cell · 1996 · 849 citations · Full text

Medicine, Molecular Genetics, Oncology +11

High TGFβ-Smad Activity Confers Poor Prognosis in Glioma Patients and Promotes Cell Proliferation Depending on the Methylation of the PDGF-B Gene

Alejandra Bruna, Rachel S. Darken, Federico Rojo et al. · Cancer Cell · 2007 · 477 citations · Full text

Medicine, Cancer Biology, Oncology +16

The SMAD4 protein and prognosis of pancreatic ductal adenocarcinoma.

Metin Tascilar, Halcyon G. Skinner, Christophe Rosty et al. · PubMed · 2001 · 310 citations

Medicine, Oncology, Pathology +17

Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: a tissue microarray study.

Wen Xie, Joachim C. Mertens, Daniel Reiss et al. · PubMed · 2002 · 217 citations

Life Sciences, Molecular Biology, Oncology +16