Three-dimensional simulation of IgG delivery to tumors

Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas

Henry Brem, Steven Piantadosi, P. C. Burger et al. · The Lancet · 1995 · 1.4K citations · Full text

Pharmacy, Oncology, Surgery +16

Transport of molecules in the tumor interstitium: a review.

PubMed · 1987 · 1.4K citations

Medicine, Cancer Biology, Oncology +17

Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy.

Yves Boucher, Laurence T. Baxter · PubMed · 1990 · 765 citations

Medicine, Oncology, Cancer Pharmacology +9

Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure.

R K Jain, Laurence T. Baxter · PubMed · 1988 · 715 citations

Medicine, Cancer Biology, Oncology +17

Bioerodible polyanhydrides as drug‐carrier matrices. I: Characterization, degradation, and release characteristics

Kam W. Leong, Brigitta C. Brott, Róbert Langer · Journal of Biomedical Materials Research · 1985 · 538 citations

Pharmacy, Pharmaceutics, Drug Delivery +16