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An approach for cloning biosynthetic genes of 2-deoxystreptamine-containing aminocyclitol antibiotics: isolation of a biosynthetic gene cluster of tobramycin from Streptomyces tenebrarius

BiosynthesisEngineeringBiotransformationBiochemistryStreptomyces TenebrariusBiosynthetic Gene ClusterSynthetic BiologyBiosynthetic GenesNatural Product BiosynthesisMicrobiologyMolecular MicrobiologyMedicineAntimicrobial ResistanceMicrobial Genetics