Concepedia

Prospective atom-based 3D-QSAR model prediction, pharmacophore generation, and molecular docking study of carbamate derivatives as dual inhibitors of AChE and MAO-B for Alzheimer’s disease

Vikas Kumar, Nidhi Chadha, Anjani K. Tiwari, Neeta Sehgal, Anil K. Mishra

Medicinal Chemistry Research · 2013 · 30 citations · 19 references

DOI

Concepts

References

19

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

Inge Grundke‐Iqbal, Khurshid Iqbal, Y C Tung et al. · Proceedings of the National Academy of Sciences · 1986 · 3.6K citations · Full text

, , +15

Atomic Structure of Acetylcholinesterase from <i>Torpedo californica</i> : A Prototypic Acetylcholine-Binding Protein

Joel L. Sussman, Michal Harel, Felix Frolow et al. · Science · 1991 · 2.7K citations

, , +17

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

Elaine K. Perry, B. E. Tomlinson, G. Blessed et al. · BMJ · 1978 · 2K citations · Full text

, , +17

PHASE: A Novel Approach to Pharmacophore Modeling and 3D Database Searching

Steven L. Dixon, Alexander M. Smondyrev, Shashidhar N. Rao · Chemical Biology & Drug Design · 2006 · 689 citations · Full text

, , +17

ULTRASTRUCTURAL STUDIES IN ALZHEIMER'S PRESENILE DEMENTIA.

Robert D. Terry, Nicholas K. Gonatas · PubMed · 1964 · 656 citations

, , +12