Concepedia

Modulation of interleukin-12 synthesis by DNA lacking the CpG motif and present in a mycobacterial cell wall complex

Mario Filion, B. Filion, Stéphanie Reader, S. Ménard, Nigel C. Phillips

Cancer Immunology Immunotherapy · 2000 · 31 citations · 31 references

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Concepts

References

31

CpG motifs in bacterial DNA trigger direct B-cell activation

Arthur Μ. Krieg, Ae‐Kyung Yi, Sara Matson et al. · Nature · 1995 · 3.5K citations

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CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.

Dennis M. Klinman, Ae‐Kyung Yi, Serge L. Beaucage et al. · Proceedings of the National Academy of Sciences · 1996 · 1.5K citations

, , +17

Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants

Mark Roman, Elena Martín‐Orozco, Justin S. Goodman et al. · Nature Medicine · 1997 · 916 citations

, , +14

Inhibition of Angiogenesis In Vivo by Interleukin 12

Emile E. Voest, B. M. Kenyon, M. OʼReilly et al. · JNCI Journal of the National Cancer Institute · 1995 · 728 citations

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Contribution of CpG motifs to the immunogenicity of DNA vaccines

Dennis M. Klinman, Galina V. Yamshchikov, Yoshiaki Ishigatsubo · The Journal of Immunology · 1997 · 512 citations · Full text

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