Concepedia

Publication | Open Access

A new angiogenesis inhibitor, FR-111142.

DOIFull Paper Access

24

Citations

10

References

1992

Year

TAKANAO OTSUKA, Toshihiro Shibata, YASUHISA TSURUMI, Shigehiro Takase, MASAKUNI OKUHARA, Hiroshi Terano, MASANOBU KOHSAKA, Hiroshi Imanaka
The Journal of Antibiotics

Abstract

FR-111142 is a new angiogenesis inhibitor produced by a fungus Scolecobasidium arenarium F-2015. FR-111142 inhibited endothelial cell proliferation in vitro and angiogenesis in the growing chick chorioallantoic membrane model in vivo. Further, FR-111142 also suppressed the solid tumor growth in mice.

References

YearCitations

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