JAMA · 1986 · 230 citations · 26 references
Public HealthBehavioral SciencesInjury PreventionCrashworthinessRisk AssessmentVehicle Safety EngineeringInjury EpidemiologyInjury RiskMotor Vehicle Injury PreventionRoad SafetyTraffic Injury PreventionTraffic SafetyAlcohol-related Injury PreventionDeformationImpaired DrivingMotor Vehicle Crash Injury PreventionPsychomotor BehaviorRoad Traffic Injury EpidemiologyRoad Traffic Injury RiskTraumatic Injury Analysis
It is well established that alcohol (ethanol) is associated with increased probability of traumatic injury. This relationship has been attributed to alcohol's impairment of judgment and psychomotor performance, leading to increased probability of an injury-producing mishap. Once an accident occurs, it is widely believed that alcohol may protect against injury. However, controlled laboratory studies using animal models indicate that alcohol exacerbates the injurious effects of trauma. In this study, detailed analysis of data from more than 1 million drivers involved in motor vehicle crashes indicates that when the effects of injury-related variables such as safety belt use, vehicle deformation, vehicle speed, driver age, and vehicle weight are taken into account, the drinking driver is more likely to suffer serious injury or death compared with the nondrinking driver. These findings do not support the widespread belief that alcohol is protective against injury, but rather indicate that alcohol increases vulnerability to injury in any given crash.
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Ethanol potentiation of central nervous system trauma
Eugene S. Flamm, Harry B. Demopoulos, Myron L. Seligman et al. · Journal of neurosurgery · 1977 · 143 citations
Medicine, Neurobiology, Neuroscience +15
Effects of ethanol ingestion on the severity and outcome of trauma
Richard E. Ward, Timothy C. Flynn, Priscilla Miller et al. · The American Journal of Surgery · 1982 · 133 citations
Pharmacy, Pharmacology, Toxicology +11
Thrombocytopenia in Alcoholics
John Lindenbaum · Annals of Internal Medicine · 1968 · 124 citations