Organic Letters · 2000 · 568 citations · 9 references
Life SciencesBiochemistryChemistryBiocatalysisCatalysisEnzymologyCatalytic MechanismsEnzyme CatalysisEnzyme KineticsIndustrial BiocatalysisMicrobial BiocatalysisAlternative Reaction MediaAqueous Reaction MediaIonic LiquidsLipase CatalysisLipasesMicrobial Lipase Activity
[reaction:see text] Candida antarctica lipase was shown to catalyze alcoholysis, ammoniolysis, and perhydrolysis reactions using the ionic liquids 1-butyl-3-methylimidazolium tetrafluoroborate or hexafluorophosphate as reaction media. Reaction rates were generally comparable with, or better than, those observed in organic media.
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Enzymatic Catalysis in Organic Media at 100°C
A. S. Zaks, Alexander M. Klibanov · Science · 1984 · 1.1K citations