Concepedia

Atherogenic effects of TNF-α and IL-6 via up-regulation of scavenger receptors

Misato Hashizume, Masahiko Mihara

Cytokine · 2012 · 110 citations · 19 references

DOI

Concepts

References

19

Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice

Maria Febbraio, Eugene A. Podrez, Jonathan D. Smith et al. · Journal of Clinical Investigation · 2000 · 1K citations · Full text

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Deletion of LOX-1 Reduces Atherogenesis in LDLR Knockout Mice Fed High Cholesterol Diet

Jawahar L. Mehta, Nobuhito Sanada, Chang Ping Hu et al. · Circulation Research · 2007 · 441 citations · Full text

, , +9

Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice

Kathryn J. Moore, Vidya Kunjathoor, Stephanie L. Koehn et al. · Journal of Clinical Investigation · 2005 · 377 citations · Full text

, , +15

IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-  and IL-17

Misato Hashizume, Naohiko Hayakawa, Masahiko Mihara · Lara D. Veeken · 2008 · 356 citations

, , +17

Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family

Masahiko Mihara, Keiko Kasutani, Makoto Okazaki et al. · International Immunopharmacology · 2005 · 323 citations

, , +14