Polymorphisms of the Core, NS3, and NS5a Proteins of Hepatitis C Virus Genotype 1b Associate With Development of Hepatocellular Carcinoma

Abstract

HCV isolates with core-Gln(70) and/or NS3-Tyr(1082) /Gln(1112) are more closely associated with HCC development compared to those with non-(Gln(70) plus NS3-Tyr(1082) /Gln(1112) ).