Evidence that the F2-isoprostane, 8-epi-prostaglandin F2α, is formed in vivo

Glomerular actions of a free radical-generated novel prostaglandin, 8-epi-prostaglandin F2 alpha, in the rat. Evidence for interaction with thromboxane A2 receptors.

Kiyohiko Takahashi, Tarek Nammour, Masao Fukunaga et al. · Journal of Clinical Investigation · 1992 · 513 citations · Full text

Pharmacy, Pharmacology, Renal Pathophysiology +12

Noncyclooxygenase oxidative formation of a series of novel prostaglandins: Analytical ramifications for measurement of eicosanoids

Jason D. Morrow, Thomas M. Harris, L. Jackson Roberts · Analytical Biochemistry · 1990 · 478 citations

Life Sciences, Biochemistry, Pharmacology +11

Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation.

Jason D. Morrow, Joseph Awad, Tatsuko Kato et al. · Journal of Clinical Investigation · 1992 · 319 citations · Full text

Life Sciences, Pharmacology, Toxicology +17

Evidence for the existence of F2-isoprostane receptors on rat vascular smooth muscle cells

Masao Fukunaga, Naomasa Makita, L. Jackson Roberts et al. · American Journal of Physiology-Cell Physiology · 1993 · 259 citations

Medicine, Biochemistry, Pharmacology +15

The F2-isoprostane, 8-epi-prostaglandin F2α, a potent agonist of the vascular thromboxane/endoperoxide receptor, is a platelet thromboxane/endoperoxide receptor antagonist

Jason D. Morrow, Tanya A. Minton, L. Jackson Roberts · Prostaglandins · 1992 · 214 citations

Medicine, Pharmacology, Cell Signaling +11