A new strategy for directed protein cleavage

Bernard Cuenoud, Theodore M. Tarasow, Alanna Schepartz

Tetrahedron Letters · 1992 · 71 citations · 25 references

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Concepts

Abstract

Attachment of a Ni(II)-glyglyhis chelate to trifluoperazine results in a molecule capable of cleaving calmodulin at a single locus upon activation with a peracid.

References

25