Characterization of Ret-Shc-Grb2 Complex Induced by GDNF, MEN 2A, and MEN 2B Mutations

Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

Anita Schuchardt, Vivette D. D’Agati, Lena Larsson-Blomberg et al. · Nature · 1994 · 1.6K citations

Signal Transduction, Receptor Tyrosine Kinase, Physiology +7

GDNF–Induced Activation of the Ret Protein Tyrosine Kinase Is Mediated by GDNFR-α, a Novel Receptor for GDNF

Shuqian Jing, Duanzhi Wen, Yanbin Yu et al. · Cell · 1996 · 1.2K citations · Full text

Transcriptional Regulation, Novel Receptor, Signal Transduction +9

Characterization of a multicomponent receptor for GDNF

James Treanor, Laurie J. Goodman, Frédéric J. de Sauvage et al. · Nature · 1996 · 1.1K citations

Multicomponent Receptor, Signal Transduction, G Protein-coupled Receptor +5

Activation of <i>RET</i> as a Dominant Transforming Gene by Germline Mutations of MEN2A and MEN2B

Massimo Santoro, Francesca Carlomagno, Alfredo Romano et al. · Science · 1995 · 835 citations

Neurturin, a relative of glial-cell-line-derived neurotrophic factor

Paul T. Kotzbauer, Patricia A. Lampe, Robert O. Heuckeroth et al. · Nature · 1996 · 715 citations

Neurodegenerative Diseases, Molecular Physiology, Neuroscience +4